"In his "Second Treatise,” John Locke maintains the natural liberty of human beings; all people are born free, and the attempt to enslave any person creates a state of war. Yet Locke himself had invested in the slave trade and drafted the Fundamental Constitutions of Carolina which granted absolute power over slaves. How do you think Locke reconciled his beliefs with his actions (if at all) regarding slavery?"
That's a tough question to answer... Often it's said that actions speak louder than words. It would seem that Locke deemed the financial gain of the slave trade to be greater than the injustice of it. Then again, it doesn't seem completely clear as to the timeline of events. For instance, John Newton, who had been the captain of a slave ship early in life only to later realize the injustice of the slave trade and change his position so completely that he then fought to abolish slavery. This very well could have been the same thing to happen to Locke.
Again, this is simply one humble opinion, so other opinions are very welcome!